R. Novak

The paper identifies SNC80 as a drug that reversibly slows metabolism in Xenopus and demonstrates its cross-species applicability in human organs-on-chips and porcine organs.

The paper identifies host tolerance mechanisms to bacterial infection using a Xenopus model and multi-omics analysis, finding that metal chelators and HIF-1 agonists enhance survival.

This paper identifies vorinostat as a potential repurposed therapy for Rett syndrome by combining computational network analysis with CRISPR-edited Xenopus models, showing efficacy across multiple organ systems.

This paper shows that the aneural protist Physarum polycephalum uses mechanosensation to preferentially grow toward heavier, chemically inert masses, revealing a novel biomechanical decision-making mechanism.

The paper introduces an automated platform for culturing and analyzing human Organ Chips, demonstrating its ability to maintain organ function and predict tracer distribution using a computational model.