A. E. Qualls

This study shows that lifelong Ulk1-mediated autophagy deficiency in muscle leads to mitochondrial dysfunction and contractile weakness in aging.

This study shows that fukutin deficiency in mice causes mitochondrial dysfunction and reduced muscle strength, which is not rescued by exercise or AICAR, but AICAR improves muscle recovery after injury.

This study investigates autophagy and mitochondrial function in skeletal muscle under different stress conditions, finding that freeze injury causes mitochondrial dysfunction and autophagy scales with injury severity.

This study shows that PGC-1α overexpression improves oxidative capacity and muscle strength in VML-injured muscle, suggesting it as a potential therapeutic target.