Author

A. Echard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 5 Approach:experimental assay· 5 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

S. Fremont· 3 shared F. Cuvelier· 2 shared M. Rocancourt· 2 shared A. Houdusse· 1 shared A. JEGOU· 1 shared A. Presle· 1 shared A. Salles· 1 shared A.-J. Jimenez· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCell Biology

S. Fremont

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cytokinetic abscission requires actin-dependent microtubule severing

T. Advedissian, S. Fremont, A. Echard

This study shows that F-actin, via Cofilin-1 and Arp2/3, promotes microtubule severing during cytokinetic abscission, independent of membrane scission.

bioRxiv · Dec 11, 2023 · PreprintCell Biology

MiniBAR/KIAA0355 is a dual Rac and Rab effector required for ciliogenesis

R. Shaughnessy, M. Serres, S. Escot, H. Hammich, F. Cuvelier, A. Salles, M. Rocancourt, Q. Verdon, A.-L. Gaffuri, Y. Sourigues, G. Malherbe, L. Velikovsky, F. Chardon, J.-Y. Tinevez, I. Callebaut, , A. Echard

This study identifies MiniBAR as a dual Rac and Rab effector essential for ciliogenesis, showing its role in coordinating actin dynamics and membrane trafficking.

bioRxiv · Jul 24, 2023 · PreprintCell Biology

Caveolae promote successful abscission by controlling intercellular bridge tension during cytokinesis

V. ANDRADE, J. Bai, N. GUPTA, A.-J. Jimenez, C. Delevoye, C. Lamaze, A. Echard

The paper shows caveolae reduce intercellular bridge tension during cytokinesis, enabling ESCRT-III assembly and successful abscission.

Science Advances · Apr 15, 2022Peer-reviewedCell Biology

Actin filament oxidation by MICAL1 suppresses protections from cofilin-induced disassembly

H. Wioland, S. Fremont, B. Guichard, A. Echard, A. JEGOU, G. Romet-Lemonne

This study shows that MICAL1-induced actin filament oxidation enhances cofilin binding and severing, bypassing the need for cofilin activation and overcoming tropomyosin protection.

bioRxiv · Feb 26, 2020Biochemistry

The Flemmingsome reveals an ESCRT-to-membrane coupling required for completion of cytokinesis

C. Addi, A. Presle, S. Fremont, F. Cuvelier, M. Rocancourt, F. Milin, S. Schmutz, J. Chamot-Rooke, T. Douche, M. Duchateau, Q. Giai Gianetto, H. Menager, M. Matondo, P. Zimmermann, N. Gupta-Rossi, A. Echard

The paper identifies a plasma membrane-to-ESCRT module essential for abscission, showing its role in cytokinesis, exosome formation, and HIV budding.

bioRxiv · Jan 15, 2020Cell Biology