Author

C. Delevoye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 7 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 8 Approach:experimental assay· 7 Organism:human· 6 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

G. Raposo· 5 shared I. Hurbain· 4 shared A. Di Cicco· 2 shared C. Lamaze· 2 shared D. Levy· 2 shared M. S. Marks· 2 shared R. A. Jani· 2 shared Y. Zhu· 2 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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5 shared papersCell Biology

G. Raposo

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

How Myosin VI Traps its Off-State, is Activated and Dimerizes

L. Canon, C. Kikuti, V. J. Planelles-Herrero, T. Lin, F. Mayeux, H. Sirkia, Y. i. Lee, L. Heidsieck, L. Velikovsky, A. David, X. Liu, D. Moussaoui, E. Forest, P. Hook, K. J. Petersen, , A. Houdusse

This study investigates how Myosin VI is trapped in its off-state, activated, and dimerizes through structural and functional analyses of its interactions with partners.

bioRxiv · Jun 30, 2023Biochemistry

The recycling endosome biogenesis machinery coordinates BACE1 endosomal sorting and amyloid-Beta production

J.-B. Brault, Z. Liu, S. Bardin, D. Ladarre, V. Fraisier, A. Tchenio, Z. Lenkei, J. Salamero, C. Delevoye, B. Goud, S. Miserey

This study identifies the recycling endosome biogenesis machinery as critical for BACE1 endosomal sorting and amyloid-beta production in Alzheimer's disease.

bioRxiv · Apr 5, 2023 · PreprintCell Biology

Caveolae promote successful abscission by controlling intercellular bridge tension during cytokinesis

V. ANDRADE, J. Bai, N. GUPTA, A.-J. Jimenez, C. Delevoye, C. Lamaze, A. Echard

The paper shows caveolae reduce intercellular bridge tension during cytokinesis, enabling ESCRT-III assembly and successful abscission.

Science Advances · Apr 15, 2022Peer-reviewedCell Biology

Dual blockade of misfolded alpha-sarcoglycan degradation by bortezomib and givinostat combination

L. Hoch, N. Bourg, F. Degrugillier, C. Bruge, M. Benabides, E. Pellier, J. Tournois, G. Mahe, N. Maignan, J. Dawe, M. Georges, D. Papazian, N. Subramanian, S. Simon, P. Fanen, , X. Nissan

This study identifies givinostat as a potential therapeutic for LGMD R3 by inhibiting autophagy and enhancing bortezomib's effect on misfolded alpha-sarcoglycan degradation.

bioRxiv · Mar 16, 2022Pharmacology & Toxicology

PI4P and BLOC-1 remodel endosomal membranes into tubules

R. A. Jani, A. Di Cicco, T. Keren-Kaplan, S. Vale-Costa, D. Hamaoui, I. Hurbain, F.-C. Tsai, M. Dimarco, A.-S. Mace, Y. Zhu, M. J. Amorim, P. Bassereau, J. S. Bonifacino, A. Subtil, M. S. Marks, , C. Delevoye

This study shows how PI4P and BLOC-1 coordinate to form and stabilize endosomal tubules, essential for membrane remodeling and pathogen trafficking.

bioRxiv · Oct 21, 2021Cell Biology

Two type II phosphatidylinositol 4-kinases function sequentially in tubule-mediated cargo delivery from early endosomes to melanosomes

Y. Zhu, S. Li, A. Jaume, R. A. Jani, C. Delevoye, G. Raposo, M. S. Marks

The paper shows that PI4KII and PI4KIIβ sequentially generate PtdIns4P to support BLOC-1-dependent tubule elongation for melanosome content delivery.

bioRxiv · Oct 19, 2021Cell Biology

Catabolism of lysosome-related organelles in color-changing spiders supports intracellular turnover of pigments

F. Figon, I. Hurbain, X. Heiligenstein, S. Trepout, K. Medjoubi, A. Somogyi, C. Delevoye, G. Raposo, J. Casas

This study examines pigment organelle catabolism in crab spiders, showing they belong to the LRO family and undergo intracellular degradation without cell death or secretion.

bioRxiv · Feb 22, 2021Cell Biology

Dynlt3, a novel fundamental regulator of melanosome movement, distribution, maturation and transfer

Z. Aktary, A. Conde, F. Rambow, M. Di Marco, F. Amblard, I. Hurbain, G. Raposo, C. Delevoye, S. Coscoy, L. LARUE

This study identifies Dynlt3 as a critical regulator of melanosome transport, maturation, and transfer in melanocytes, revealing its role in skin pigmentation through interactions with the Wnt/β-catenin pathway.

bioRxiv · Jan 13, 2021 · PreprintCell Biology

Caveolae coupling of melanocytes signaling and mechanics is required for human skin pigmentation

L. Domingues, I. Hurbain, F. Gilles-Marsens, N. Andre, M. Dewulf, M. Romao, C. Viaris de Lesegno, C. Blouin, C. Guere, K. Vie, G. Raposo, C. Lamaze, C. Delevoye

This study shows that caveolae in melanocytes couple signaling from keratinocytes to mechanical changes, essential for skin pigmentation and tissue homeostasis.

bioRxiv · Jun 10, 2019Cell Biology