Evolutionary BiologybioRxiv
Epistasis between promoter activity and coding mutations shapes gene evolvability
A. F. C. Caballero, I. Gagnon-Arsenault, A. K. Dube…·C. R. Landry
The paper shows that expression level masks the effects of coding mutations, demonstrating that expression level dictates their fitness impact.
DOI 10.1126/sciadv.add9109