A. Ganesh

Salmonella Typhimurium infection inhibits macrophage IFNbeta signaling in a TLR4-dependent manner

This study shows Salmonella Typhimurium inhibits macrophage IFNbeta signaling via TLR4, but IFNbeta does not affect host defense against STm.

Targeted hypermutation of putative antigen sensors in multicellular bacteria

The paper shows multicellular bacteria use DGRs to diversify antigen sensors, enhancing adaptive immunity and supporting the evolution of multicellularity.

Diversity at single nucleotide to pangenome scales among sulfur cycling bacteria in salt marshes

This study characterizes sulfur-cycling microbial diversity in salt marshes using metagenomics, revealing genomic variation across sites and plant species.

Modification of blood-based (IgG) to salivary-based (IgA) ELISA for Inflammatory Bowel Disease Diagnostic: Tumor necrosis factor (TNF) alpha quantification

This paper modifies a blood-based ELISA to a salivary-based ELISA for TNF-alpha quantification in IBD, finding reduced sensitivity but improved accessibility.

A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters

This study evaluates a SARS-CoV-2 spike ferritin nanoparticle vaccine's effectiveness against B.1.1.7 and B.1.351 variants in hamsters, showing protection against disease and viral replication.