Human spermatogonial stem cells retain states with a foetal-like signature
S. J. Bush, R. Nikola, S. Han, S. Suzuki, S. Yoshida, B. D. Simons, A. Goriely
This study identifies a foetal-like state 0B in human spermatogonial stem cells that maintains a suppressive transcriptomic program, contrasting with rodent models where this state is not maintained into adulthood.
bioRxiv · Mar 18, 2024Cell Biology