Author

A. Graf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1 Assay:CRISPR screen· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

F. Kirchhoff· 4 shared H. Blum· 4 shared S. Krebs· 4 shared A. Schundner· 3 shared C. Prelli Bozzo· 3 shared D. Kmiec· 3 shared F. Zech· 3 shared L. Koepke· 3 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

F. Kirchhoff

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Traitor-virus-guided discovery of novel antiviral factors

C. Prelli Bozzo, A. Laliberte, A. De Luna, C. Pastorio, K. Regensburger, S. Krebs, A. Graf, H. Blum, M. Volcic, K. M. Sparrer, F. Kirchhoff

This study uses HIV-guided CRISPR to identify antiviral factors by analyzing sgRNA enrichment during viral replication.

bioRxiv · Nov 3, 2023 · PreprintMicrobiology

SARS-CoV-2 variants of concern are dependent on IFITM2 for efficient replication in human lung cells

R. Nchioua, A. Schundner, D. Kmiec, C. Prelli Bozzo, F. Zech, L. Koepke, A. Graf, S. Krebs, H. Blum, M. Frick, K. M. J. Sparrer, F. Kirchhoff

The paper was withdrawn due to duplicate submission and is not intended for citation.

bioRxiv · Dec 6, 2021 · PreprintImmunology

SARS-CoV-2 variants of concern remain dependent on IFITM2 for efficient replication in human lung cells

R. Nchioua, A. Schundner, D. Kmiec, C. Prelli Bozzo, F. Zech, L. Koepke, A. Graf, S. Krebs, H. Blum, M. Frick, K. M. Sparrer, F. Kirchhoff

This study shows that SARS-CoV-2 variants of concern (VOCs) require IFITM2 for efficient replication in human lung cells, with IFITM2 depletion reducing viral RNA and infectious virus production by over four orders of magnitude.

bioRxiv · Nov 17, 2021 · PreprintMicrobiology

The Delta variant of SARS-CoV-2 maintains high sensitivity to interferons in human lung cells

R. Nchioua, A. Schundner, S. Klute, S. Noettger, F. Zech, L. Koepke, A. Graf, S. Krebs, H. Blum, D. Kmiec, M. Frick, F. Kirchhoff, K. Sparrer

This study examines IFN sensitivity of SARS-CoV-2 variants, finding Delta remains as sensitive as early isolates, while Alpha, Beta, and Gamma show increased resistance.

bioRxiv · Nov 16, 2021Microbiology

Photoperiodic control of the Arabidopsis proteome reveals a translational coincidence mechanism

D. Seaton, A. Graf, K. Baerenfaller, M. Stitt, A. Millar, W. Gruissem

The paper quantifies the Arabidopsis proteome across photoperiods, identifies translational coincidence as a mechanism for photoperiodic protein regulation, and shows its conservation in other phototrophic organisms.

bioRxiv · Aug 29, 2017Plant Biology