Author

A. Graziadei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:imaging· 1 Organism:non-human primate· 1

Frequent Co-Authors

J. Rappsilber· 4 shared C. Gotthold· 2 shared C. M. T. Spahn· 2 shared D. Schwefel· 2 shared S. Banchenko· 2 shared T. Mielke· 2 shared A. Chauvier· 1 shared A. Malyshkina· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersBiochemistry

J. Rappsilber

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular basis of mRNA delivery to the bacterial ribosome

M. W. Webster, A. Chauvier, H. Rahil, A. Graziadei, K. Charles, M. Takacs, C. Saint-Andre, J. Rappsilber, N. G. Walter, A. Weixlbaumer

This study investigates how bS1 facilitates mRNA delivery to the ribosome and enhances translation initiation by RNAP in bacteria.

bioRxiv · Mar 19, 2024Biochemistry

The sterol transporter STARD3 transports sphingosine at ER-lysosome contact sites

P. Hempelmann, F. Lolicato, A. Graziadei, R. D. R. Brown, S. Spiegel, J. Rappsilber, W. Nickel, D. Höglinger, D. Jamecna

The paper identifies STARD3 as a sphingosine transporter at ER-lysosome contact sites, showing its role in sphingosine integration into ceramide.

bioRxiv · Sep 18, 2023 · PreprintCell Biology

Structure and mechanism of a novel cytomegaloviral DCAF mediating interferon antagonism

V. T. K. Le-Trilling, S. Banchenko, D. Paydar, P. M. Leipe, L. Binting, S. Lauer, A. Graziadei, C. Gotthold, J. Burger, T. Bracht, B. Sitek, R. J. Lebbink, A. Malyshkina, T. Mielke, J. Rappsilber, , D. Schwefel

This study identifies E27 as a viral protein that targets STAT2 for degradation via CRL4 ubiquitin ligases, revealing its structural mechanism of interferon antagonism.

bioRxiv · May 5, 2022Biochemistry

Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses

S. Banchenko, F. Krupp, C. Gotthold, J. Buerger, A. Graziadei, F. O' Reilly, L. Sinn, O. Ruda, J. Rappsilber, C. M. T. Spahn, T. Mielke, I. A. Taylor, D. Schwefel

This paper investigates how SIVmus Vpr interacts with CRL4DCAF1 to ubiquitylate SAMHD1, revealing structural and mechanistic insights into viral counteraction of host restriction factors.

bioRxiv · Dec 31, 2020Biochemistry