Author

S. Lauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:long-read sequencing· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. Graziadei· 1 shared A. Malyshkina· 1 shared B. Sitek· 1 shared C. Gotthold· 1 shared C. M. T. Spahn· 1 shared D. Gresham· 1 shared D. Paydar· 1 shared D. Schwefel· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Graziadei

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2 papers

Recent·Most cited

Structure and mechanism of a novel cytomegaloviral DCAF mediating interferon antagonism

V. T. K. Le-Trilling, S. Banchenko, D. Paydar, P. M. Leipe, L. Binting, S. Lauer, A. Graziadei, C. Gotthold, J. Burger, T. Bracht, B. Sitek, R. J. Lebbink, A. Malyshkina, T. Mielke, J. Rappsilber, , D. Schwefel

This study identifies E27 as a viral protein that targets STAT2 for degradation via CRL4 ubiquitin ligases, revealing its structural mechanism of interferon antagonism.

bioRxiv · May 5, 2022Biochemistry

Single-cell copy number variant detection reveals the dynamics and diversity of adaptation

S. Lauer, G. Avecilla, P. Spealman, G. Sethia, N. Brandt, S. Levy, D. Gresham

This study detects single-cell copy number variants (CNVs) in evolving populations and identifies ODIRA as a common mechanism for gene amplification.

bioRxiv · Jul 31, 2018Evolutionary Biology