Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
M. G. Alteen, J. C. Deme, C. P. Alvarez…·R. J. Harding
This paper develops validated HTT subdomain constructs for biochemical and structural studies of huntingtin protein interactions and function.
B. J. Fraser, S. Beldar, A. Seitova…·F. Benard
This study characterizes the structure and function of TMPRSS2, a protease involved in SARS-CoV-2 activation, and identifies features for developing selective inhibitors.
R. J. Harding, J. C. Deme, J. F. Hevler…·C. H. Arrowsmith
This study reveals how HAP40 orchestrates HTT structure, affecting its interaction with polyglutamine-expanded exon 1, providing insights into Huntington's disease mechanisms.
R. J. Harding, P. Loppnau, S. Ackloo…·C. Arrowsmith
This paper develops a toolkit for producing mutant and wild-type huntingtin proteins in eukaryotic systems to enable biochemical and structural studies of HD-related mutations.