Author

S. Beldar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Hutchinson· 2 shared A. Seitova· 2 shared C. H. Arrowsmith· 2 shared L. Halabelian· 2 shared Y. Li· 2 shared A. Bolotokova· 1 shared A. Dong· 1 shared A. K. Yazdi· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

A. Hutchinson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A resource to enable chemical biology and drug discovery of WDR Proteins

C. H. Arrowsmith, S. Ackloo, F. Li, M. Szewczyk, A. Seitova, P. Loppnau, H. Zeng, S. Ahmad, S. Beldar, A. Bolotokova, I. Chau, S. Dehghani-Tafti, A. Dong, P. Ghiabi, E. Gibson, , Arnautova

The paper develops a resource for discovering ligands for WDR proteins using experimental and computational methods, leading to the identification of drug-like ligands for 9 out of 20 targets.

bioRxiv · Mar 3, 2024Biochemistry

Structure, activity and inhibition of human TMPRSS2, a protease implicated in SARS-CoV-2 activation

B. J. Fraser, S. Beldar, A. Seitova, A. Hutchinson, D. Mannar, Y. Li, D. Kwon, R. Tan, R. P. Wilson, K. Leopold, S. Subramaniam, L. Halabelian, C. H. Arrowsmith, F. Benard

This study characterizes the structure and function of TMPRSS2, a protease involved in SARS-CoV-2 activation, and identifies features for developing selective inhibitors.

bioRxiv · Jun 23, 2021Biochemistry