Author

J. F. Hevler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. J. R. Heck· 3 shared A. Cabrera-Orefice· 1 shared A. Hutchinson· 1 shared A. J. Heck· 1 shared A. Jankevics· 1 shared A. Lemak· 1 shared A. Potter· 1 shared A. Seitova· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBiochemistry

A. J. R. Heck

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Author profile →

4 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 8, 2022

MRPS36 provides a missing link in the eukaryotic 2-oxoglutarate dehydrogenase complex for recruitment of E3 to the E2 core

J. f. Hevler, P. Albanese, A. Cabrera-Orefice…·A. J. R. Heck

The paper identifies MRPS36 as an essential component of the eukaryotic 2-oxoglutarate dehydrogenase complex, replacing the bacterial PSBD and providing structural insights into its organization.

DOI 10.1101/2022.10.08.511390

mousemultiple species

𝕏 PostBluesky

BiochemistrybioRxivMay 16, 2022

Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly

E. S. Fischer, C. W. Yu, J. F. Hevler…·D. Barford

This study investigates how Mps1 phosphorylation of Mad1 facilitates the assembly of the mitotic checkpoint complex by promoting interactions between Mad1, Cdc20, and Bub1.

DOI 10.1038/s41467-022-34058-2

protein structureprotein sequence

𝕏 PostBluesky

BiochemistrybioRxivApr 2, 2021

HAP40 orchestrates huntingtin structure for differential interaction with polyglutamine expanded exon 1

R. J. Harding, J. C. Deme, J. F. Hevler…·C. H. Arrowsmith

This study reveals how HAP40 orchestrates HTT structure, affecting its interaction with polyglutamine-expanded exon 1, providing insights into Huntington's disease mechanisms.

DOI 10.1038/s42003-021-02895-4

humanstructural biology

𝕏 PostBluesky

Cell BiologybioRxivPreprintFeb 16, 2021

In-cell structures of a conserved supramolecular array at the mitochondria-cytoskeleton interface in mammalian sperm

M. R. Leung, R. Zenezini Chiozzi, M. Roelofs…·T. Zeev-Ben-Mordehai

The paper uses cryo-electron tomography to image mitochondria-cytoskeleton interfaces in mammalian sperm, revealing conserved supramolecular arrays composed of glycerol kinase-like proteins.

DOI 10.1101/2021.02.16.431372

mousecryo-EM

𝕏 PostBluesky