BiophysicsbioRxivPreprint
Decoding Angiotensin II Type 1 Receptor Allosteric Communication to Gq and β-arrestin
A. K. Nivedha, Y. Cao, S. Lee…·N. Vaidehi
This study identifies residue networks mediating allosteric communication from the Ang II binding site to Gq and β-arrestin2 coupling sites in AT1R, revealing shared and distinct residues that could guide biased ligand design.
DOI 10.1101/2021.05.17.444454