Author

A. Korennykh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

S. Rath· 4 shared J. Donovan· 3 shared A. Chitrakar· 2 shared E. Prangley· 2 shared J. Du· 2 shared K. Demarest· 2 shared N. Wingreen· 2 shared D. Kolet-Mandrikov· 1 shared

Activity by Year

2016-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersCell Biology

S. Rath

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The Metabolites NADP+ and NADPH are the Targets of the Circadian Protein Nocturnin (Curled)

M. A. Estrella, J. Du, L. Chen, S. Rath, E. Prangley, A. Chitrakar, T. Aoki, P. Schedl, J. Rabinowitz, A. Korennykh

This study identifies NADP+ and NADPH as substrates of the circadian protein Nocturnin, showing its enzymatic activity in converting these metabolites and revealing structural insights into its mechanism.

bioRxiv · Jan 30, 2019Biophysics

Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in dsRNA Response

S. Rath, E. Prangley, J. Donovan, K. Demarest, Y. Meir, N. Wingreen, A. Korennykh

The paper investigates how 2-5A-mediated mRNA decay and transcription reprogram protein synthesis in response to dsRNA, showing that IFN-related mRNAs accumulate due to stability and feedback mechanisms.

bioRxiv · Dec 4, 2018Cell Biology

Realtime 2-5A kinetics suggests interferons β and {lambda} evade global arrest of translation by RNase L

A. Chitrakar, S. Rath, J. Donovan, K. Demarest, Y. Li, R. Rao Sridhar, S. Weiss, S. Kotenko, N. Wingreen, A. Korennykh

The paper develops a biosensor to study 2-5A kinetics and shows that interferons β and λ evade RNase L-mediated translation arrest during the innate immune response.

bioRxiv · Nov 26, 2018Cell Biology

Crystal Structure of Human Nocturnin Catalytic Domain

M. Estrella, J. Du, A. Korennykh

The paper presents the crystal structure of the human Nocturnin catalytic domain and identifies structural differences from related deadenylases.

bioRxiv · May 27, 2018Biophysics

Y-RNA and tRNA Cleavage by RNase L Mediates Terminal dsRNA Response

J. Donovan, S. Rath, D. Kolet-Mandrikov, A. Korennykh

The paper identifies RNase L as the enzyme responsible for cleaving Y-RNAs and tRNAs in response to dsRNA, with RNY1 depletion initiating apoptosis.

bioRxiv · Nov 10, 2016Immunology