BiophysicsbioRxiv
The Metabolites NADP+ and NADPH are the Targets of the Circadian Protein Nocturnin (Curled)
M. A. Estrella, J. Du, L. Chen…·A. Korennykh
This study identifies NADP+ and NADPH as substrates of the circadian protein Nocturnin, showing its enzymatic activity in converting these metabolites and revealing structural insights into its mechanism.
DOI 10.1038/s41467-019-10125-z