ImmunologybioRxivPreprint
Recognition of Z-RNA by ADAR1 limits interferon responses
Q. Tang, R. E. Rigby, G. R. Young…·J. Rehwinkel
This study shows that ADAR1's Z domain prevents IFN responses by recognizing Z-RNA, and its absence leads to spontaneous IFN induction and improved viral control.
DOI 10.1101/2020.12.04.411793