Author

A. Lackner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Beyer· 1 shared A. Chugunova· 1 shared A. Macapagal· 1 shared A. Panganiban· 1 shared A. Pauli· 1 shared A. Singapuri· 1 shared A. Smith· 1 shared A. von Haeseler· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. Beyer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Small molecule inhibitor binds to NLRP3 and prevents inflammasome activation

A. Lackner, J. E. Cabral, Y. Qiu, H. Zhou, L. Leonidas, M. A. Pham, A. Macapagal, S. Lin, E. Armanus, R. McNulty

The paper identifies that NLRP3 binds and cleaves oxidized DNA, and small molecule drugs inhibit this process to prevent inflammasome activation.

bioRxiv · Dec 13, 2023Immunology

NMD is required for timely cell fate transitions by fine-tuning gene expression and controlling translation

E. Galimberti, R. Sehlke, M. Huth, M. Garmhausen, M. Romeike, J. Ramesmayer, S. Stummer, F. Titz-Teixeira, V. Herzog, A. Chugunova, K. F. Leesch, L. Holcik, L. Santini, A. Lackner, A. von Haeseler, , M. Leeb

This study shows NMD regulates cell fate transitions by controlling Eif4a2 translation and revealing a hierarchy in Smg5, Smg6, and Smg7 functions.

bioRxiv · Jul 7, 2020Cell Biology

Maternal antibodies provide partial protection from postnatal Zika viremia in nonhuman primates

N. Maness, B. Schouest, A. Singapuri, M. Dennis, M. Gilbert, R. Bohm, F. Schiro, P. Aye, K. Baker, K. Van Rompay, A. Lackner, M. Bonaldo, R. Blair, S. Permar, L. Coffey, , D. Magnani

This study shows that maternal antibodies provide partial protection against postnatal Zika virus infection in infant nonhuman primates, reducing viremia but not completely preventing viral dissemination.

bioRxiv · Apr 18, 2019Microbiology