M. Gilbert

A 20+ Ma old enamel proteome from Canada's High Arctic reveals diversification of Rhinocerotidae in the middle Eocene-Oligocene

This paper retrieves ancient enamel protein sequences from a 21-24 Ma rhinocerotid, providing new phylogenetic insights into Rhinocerotidae diversification during the middle Eocene-Oligocene.

Mid-Cenozoic Rhinocerotid Dispersal via the North Atlantic

The paper describes a new Early Miocene rhinocerotid species from the Canadian High Arctic and presents phylogenetic hypotheses, suggesting the North Atlantic Land Bridge was crossable for mammals longer than previously thought.

SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging

This study identifies NUCKS1 as a novel SIRT7 interactor that promotes chromatin binding during senescence and liver aging, leading to metabolic and inflammatory gene expression.

Protective effect of pre-existing natural immunity in a nonhuman primate reinfection model of congenital cytomegalovirus infection

This study shows that pre-existing CMV immunity in nonhuman primates reduces placental transmission and fetal loss during reinfection compared to primary infection.

BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved antitumor activity

This paper evaluates BOXR1030, a CAR T cell therapy co-expressing GPC3-targeted CAR and GOT2, showing enhanced T cell metabolism and improved antitumor activity in preclinical models.

Phylogeographic and phylodynamic approaches to epidemiological hypothesis testing

This study uses phylogeographic and phylodynamic methods to test hypotheses about West Nile virus dispersal and genetic diversity, finding temperature influences on spread and no strong evidence for migratory bird flyway restriction.

Coronavirus testing indicates transmission risk increases along wildlife supply chains for human consumption in Viet Nam, 2013-2014

The paper detects coronaviruses in wildlife along supply chains in Viet Nam, finding higher prevalence in animals sold in markets and restaurants, suggesting increased transmission risk to humans.

A phylodynamic workflow to rapidly gain insights into the dispersal history and dynamics of SARS-CoV-2 lineages

This paper introduces a phylodynamic workflow to analyze SARS-CoV-2 lineage dispersal, showing external introductions were key in Belgium and lockdowns had limited impact on transmission.

Coronavirus surveillance of wildlife in the Lao People's Democratic Republic detects viral RNA in rodents

The paper detects Betacoronavirus RNA in 12 rodents from Laos, belonging to two genetic clusters related to regional rodent coronaviruses and distantly to human coronaviruses.

Downscaling livestock census data using multivariate predictive models: sensitivity to modifiable areal unit problem

This study evaluates how the modifiable areal unit problem affects downscaling livestock census data, finding that scale impacts precision more than shape or sampling method.

Maternal antibodies provide partial protection from postnatal Zika viremia in nonhuman primates

This study shows that maternal antibodies provide partial protection against postnatal Zika virus infection in infant nonhuman primates, reducing viremia but not completely preventing viral dissemination.

Genetics behind the biosynthesis of nonulosonic acid containing lipooligosaccharides in Campylobacter coli

This study identifies the role of CstIV and CstV in C. coli lipooligosaccharide biosynthesis, showing cstV is involved in sialylation and cstIV in adding a diacetylated nonulosonic acid residue.

Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys

This study shows that preexisting antibodies can prevent congenital cytomegalovirus infection in monkeys by blocking placental transmission.