Author

A. Lafferty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Bertotti· 1 shared A. C. O'Farrell· 1 shared A. L. Welm· 1 shared A. Srivastava· 1 shared A. V. Kossenkov· 1 shared B. Davis-Dusenbery· 1 shared B. E Welm· 1 shared C. Frech· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Bertotti

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Orally administered epeleuton inhibits SARS-CoV-2 viral load, replication and pathology in the Syrian Hamster model

J. Climax, M. Hamza, A. Lafferty, K. Guilfoyle, G. van Amerongen, K. Stadler, P. Wohlsein, W. Baumgärtner, M. Weissbach, D. Coughlan

This study shows that epeleuton reduces SARS-CoV-2 viral load, replication, and lung pathology in Syrian hamsters when administered orally.

bioRxiv · Dec 7, 2021 · PreprintMicrobiology

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

X. Y. Woo, J. Giordano, A. Srivastava, Z.-M. Zhao, M. W. Lloyd, R. de Bruijn, Y.-S. Suh, R. Patidar, L. Chen, S. Scherer, M. Bailey, C.-H. Yang, E. Cortes-Sanchez, Y. Xi, J. Wang, , B. E Welm

This study shows that copy number profiles are conserved in patient-derived xenografts (PDXs) through engraftment and passaging, indicating minimal impact from the mouse host on tumor evolution.

bioRxiv · Dec 3, 2019Cancer Biology