Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection
R. A. Flynn, J. A. Belk, Y. Qi, Y. Yasumoto, C. O. Schmitz, M. R. Mumbach, A. Limaye, J. Wei, M. M. Alfajaro, K. R. Parker, H. Y. Chang, T. L. Horvath, J. E. Carette, C. Bertozzi, C. B. Wilen, A. T. Satpathy
This study identifies 309 host proteins interacting with SARS-CoV-2 RNA during infection and reveals their roles in virus-induced cell death and mitochondrial dysfunction.
bioRxiv · Oct 6, 2020 · PreprintMicrobiology