M. M. Alfajaro

This study shows that SARS-CoV-2 variants differ in syncytia formation, which affects host chromatin accessibility, cellular senescence, and inflammation via TP53.

This study shows DYRK1A promotes viral entry of SARS-CoV, SARS-CoV-2, and MERS-CoV by regulating ACE2 and DPP4 transcription without its kinase activity.

The paper shows that high-affinity, neutralizing antibodies against SARS-CoV-2 can be produced without T follicular helper cells through alternative pathways.

This study identifies 309 host proteins interacting with SARS-CoV-2 RNA during infection and reveals their roles in virus-induced cell death and mitochondrial dysfunction.

This study investigates the effect of NSAIDs on SARS-CoV-2 infection and finds that COX-2 is induced by the virus but NSAIDs do not impact viral entry or replication.

This study uses a Cd300lf conditional knockout mouse to show that CD300lf on tuft cells is essential for persistent MNoVCR6 infection, while myelomonocytic cells are major targets for non-persistent MNoVCW3, with STAT1 restricting its tropism.

This study investigates SARS-CoV-2 neuroinvasion in human and mouse brains using organoids, in vivo models, and autopsies, finding evidence of neuronal infection and its consequences.