K. Ward

Oxygen carrying nanoemulsions and respiratory hyperoxia eliminate tumor hypoxia-induced suppression and improve cancer immunotherapy

This study shows oxygen-carrying nanoemulsions and respiratory hyperoxia reduce tumor hypoxia, enhance T cell and NK cell infiltration, and improve cancer immunotherapy outcomes.

Mesothelial cells exhibit characteristics of perivascular cells in an in vitro angiogenesis assay

This study shows mesothelial cells can adopt a perivascular phenotype and support angiogenesis in vitro by aligning with endothelial networks and upregulating pericyte markers.

Conserved allomorphs of MR1 drive specificity of MR1-restricted TCRs

The paper shows that MR1-restricted TCRs recognize an allelic variant of MR1 (MR1*04) present in healthy individuals, indicating that these TCRs are not cancer-specific and may react to both cancer and healthy cells.

Home-field advantage affects the local adaptive interaction between Andropogon gerardii ecotypes and rhizobiome

This study shows that Andropogon gerardii ecotypes have a home-field advantage in recruiting rhizosphere microbes adapted to their local environments, supporting the home field advantage hypothesis.

Novel Complete Methanogenic Pathways in Longitudinal Genomic Study of Monogastric Age-Associated Archaea

This study identifies novel methanogenic pathways in swine archaea across age, revealing acetoclastic methanogenesis in monogastric archaea and their presence across multiple hosts and time periods.

ROCK2 Knockout Improves Proliferation Rate in a Cellular Model of Down Syndrome

ROCK2 knockout improves cell proliferation in a trisomy 21 cellular model of Down Syndrome, with no effect in euploid cells.

Culturomics of Andropogon gerardii rhizobiome revealed nitrogen transforming capabilities of stress-tolerant Pseudomonas under drought conditions

The study identifies stress-tolerant Pseudomonas in the rhizobiome of Andropogon gerardii under drought, revealing nitrogen transformation capabilities that may support plant growth.

Stability and volatility shape the gut bacteriome and mycobiome dynamics in a pig model

This study examines gut microbiome dynamics in pigs, identifying distinct bacterial and fungal patterns across developmental stages and their correlations.

THE LIFESPAN AND OXIDATIVE STRESS BETWEEN FERAL AND MANAGED HONEY BEE COLONIES

This study compares lifespan and oxidative stress levels between feral and managed honey bee colonies, finding feral bees live longer but show higher oxidative stress, suggesting tolerance rather than repair mechanisms.

Characterisation of a novel ACE2-based therapeutic with enhanced rather than reduced activity against SARS-CoV2 variants

The paper characterizes a novel ACE2-based therapeutic that effectively neutralizes SARS-CoV-2 variants and demonstrates antibody-like properties and manufacturability.

Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning

The paper develops a gene signature using exosomal RNA from canine osteosarcoma xenografts and machine learning to detect residual disease in dogs, showing improved remission outcomes in validation samples.