SS-31 Reverses Mitochondrial Fragmentation in Fibroblasts from Patients with DCMA, a Mitochondrial Cardiomyopathy
P. Machiraju, X. Wang, R. Sabouny, J. Huang, T. Zhao, F. Iqbal, M. King, D. Prasher, A. Lodha, A. Ravandi, B. Argiropoulos, D. Sinasac, A. Khan, T. Shutt, S. C. Greenway
This study shows that SS-31 reverses mitochondrial fragmentation and increases ROS in DCMA fibroblasts, suggesting it as a potential therapy for this mitochondrial cardiomyopathy.
bioRxiv · Jun 17, 2019Cell Biology