PhysiologybioRxiv
Modulation of the Cardiac Sodium Channel Nav1.5 Peak and Late Currents by NAD+ Precursors
D. Matasic, J.-Y. Yoon, J. M. McLendon…·B. London
This study investigates how NAD+ precursors NR and NAM affect NaV1.5 currents and cardiac electrophysiology, finding NR increases peak INa and reduces INa,L while NAM has mixed effects.