Author

A. M. Langmüller

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Evolutionary Biology· 1

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Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. G. Clark· 1 shared J. Champer· 1 shared J. Liu· 1 shared L. Xie· 1 shared M. Metzloff· 1 shared P. W. Messer· 1 shared S. Lapinska· 1 shared Y. Xu· 1 shared

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2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperEvolutionary Biology

A. G. Clark

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1 paper

Recent·Most cited

Evolutionary BiologybioRxivMay 13, 2021

Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations

A. M. Langmüller, J. Champer, S. Lapinska…·P. W. Messer

This study evaluates fitness costs of CRISPR/Cas9 in Drosophila by tracking allele frequencies of transgenic constructs, finding moderate off-target costs but no direct Cas9 costs, with Cas9HF1 minimizing off-target effects.

DOI 10.7554/elife.71809

Drosophilastatistical model

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