Author

A. M. Melnick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Meydan· 2 shared A. Beheshti· 1 shared A. C. Borczuk· 1 shared A. Chadburn· 1 shared A. Corvelo· 1 shared A. Craney· 1 shared A. J. Kriegel· 1 shared A. Saravia-Butler· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

C. Meydan

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2 papers

Recent·Most cited

Cancer BiologybioRxivFeb 13, 2023

Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas

J. Li, C. R. Chin, H.-Y. Ying…·A. M. Melnick

This study shows that combined loss of CREBBP and KMT2D disrupts super-enhancer function in B cells, leading to immune evasion and T cell depletion in lymphomas.

DOI 10.1038/s41467-024-47012-1

mousehuman

𝕏 PostBluesky

MicrobiologybioRxivPreprintMar 8, 2021

Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps

J. Park, J. Foox, T. Hether…·Schwar

This study identifies systemic tissue and cellular disruption from SARS-CoV-2 infection using autopsy and spatial omics data, showing tissue-specific damage and transcriptional changes.

DOI 10.1101/2021.03.08.434433

humanbulk RNA-seq

𝕏 PostBluesky