Author

A. Chadburn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2

Frequent Co-Authors

C. Meydan· 2 shared A. Angelin· 1 shared A. Behdad· 1 shared A. Borczuk· 1 shared A. Daman· 1 shared A. E. Calvert· 1 shared A. Lin· 1 shared A. M. Melnick· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

C. Meydan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Lethal COVID-19 Associates With RAAS-Induced Inflammation For Multiple Organ Damage Including Mediastinal Lymph Nodes

J. W. Guarnieri, M. Topper, K. Beigel, J. A. Haltoom, A. Chadburn, J. Frere, J. An, H. Cope, A. Borczuk, S. Sinha, C. Lim, J. Kim, J. Park, C. Meydan, J. Foox, , K Clark

This study identifies non-canonical genes linked to RAAS overactivation in lethal COVID-19, causing multi-organ damage and mediastinal lymph node dysfunction.

bioRxiv · Oct 8, 2023 · PreprintImmunology

Locus specific human endogenous retroviruses reveal new lymphoma subtypes

B. Singh, N. Dopkins, T. Fei, J. L. Marston, S. Michael, H. Reyes-Gopar, G. Curty, J. J. Heymann, A. Chadburn, P. Martin, F. E. Leal, E. Cesarman, D. F. Nixon, M. L. Bendall

The paper identifies unique HERV signatures in B-cell lymphoma subtypes that can improve classification and diagnosis when combined with gene expression.

bioRxiv · Jun 8, 2023Cancer Biology

Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas

J. Li, C. R. Chin, H.-Y. Ying, C. Meydan, M. R. Teater, M. Xia, P. Farinha, K. Takata, C.-S. Chu, M. A. Rivas, A. Chadburn, C. Steidl, D. W. Scott, R. G. Roeder, C. E. Mason, , A. M. Melnick

This study shows that combined loss of CREBBP and KMT2D disrupts super-enhancer function in B cells, leading to immune evasion and T cell depletion in lymphomas.

bioRxiv · Feb 13, 2023Cancer Biology

Epigenetic Memory of COVID-19 in Innate Immune Cells and Their Progenitors

J. G. Cheong, A. Ravishankar, S. Sharma, C. Parkhurst, D. Nehar-Belaid, S. Ma, L. Paddock, B. Fatou, E. Karakaslar, A. Thibodeau, M. Bale, V. Kartha, J. Yee, M. Y. Mays, L. Leyre, , S. Josefowicz

The paper identifies sustained epigenomic changes in hematopoietic stem and progenitor cells after COVID-19, which influence innate immune cell function and inflammation.

bioRxiv · Feb 9, 2022Immunology

Targeting Scavenger Receptor Type B1 In Cholesterol-Addicted Lymphomas Abolishes Glutathione Peroxidase 4 and Results in Ferroptosis

J. S. Rink, A. Lin, K. M. McMahon, A. E. Calvert, S. Yang, T. Taxter, J. Moreira, A. Chadburn, A. Behdad, R. Karmali, C. S. Thaxton, L. I. Gordon

This study shows that targeting SCARB1 with HDL NPs in cholesterol-dependent lymphoma cells reduces GPX4, leading to ferroptosis and cell death.

bioRxiv · Jun 16, 2020 · PreprintCancer Biology