Cell BiologybioRxivPreprint
Structure and mechanism of TRAPPIII-mediated Rab1 activation
A. M. N. Joiner, B. P. Phillips, K. Yugandhar…·J. C. Fromme
This study determines the cryo-EM structure of the yeast TRAPPIII complex bound to Rab1/Ypt1, revealing that Trs85 anchors the complex to membranes via an amphipathic helix to activate Rab1.