Author

A. Marcu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:proteomics· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Stevanovic· 5 shared H. Schuster· 3 shared A. Nelde· 2 shared H.-G. Rammensee· 2 shared L. Bichmann· 2 shared M. Ghosh· 2 shared M. W. Loeffler· 2 shared O. Kohlbacher· 2 shared

Activity by Year

2018-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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5 shared papersImmunology

S. Stevanovic

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Author profile →

5 papers

Recent·Most cited

Global Analysis of the Mammalian MHC class I Immunopeptidome at the Organism-Wide Scale

P. Kubiniok, A. Marcu, L. Bichmann, L. Kuchenbecker, H. Schuster, D. Hamelin, J. Despault, K. Kovalchik, L. Wessling, O. Kohlbacher, S. Stevanovic, R. Hans-Georg, M. C. Neidert, I. Sirois, E. Caron

The paper analyzes the MHC class I immunopeptidome across human and mouse tissues, identifying tissue-specific and -independent peptide properties and hyperconserved protein sources.

bioRxiv · Sep 28, 2020 · PreprintImmunology

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

Z. A. Bittner, X. Liu, S. Shankar, A. Tapia Abellan, H. Kalbacher, L. Andreeva, M. Mangan, P. Duewell, M. Lovotti, K. Bosch, S. Dickhoefer, A. Marcu, S. Stevanovic, F. Herster, M. W. Loeffler, , A. N. Weber

The paper shows BTK modulates NLRP3 inflammasome activity through phosphorylation of tyrosine residues, affecting localization, oligomerization, and IL-1β release.

bioRxiv · Jun 25, 2020Immunology

An innovative approach for HLA typing, molecular tumor testing and the validation of tumor exclusive antigens

M. Ghosh, L. Bichmann, J. Scheid, G. Gueler, H. Schuster, M. Di Marco, A. Marcu, M. Beyer, A. Nelde, L. K. Freudenmann, L. Muehlenbruch, M. W. Loeffler, O. Kohlbacher, H.-G. Rammensee, S. Stevanovic

The paper describes an innovative approach for HLA typing, molecular tumor testing, and validation of tumor-exclusive antigens but has been withdrawn by the authors.

bioRxiv · Jun 5, 2020 · PreprintImmunology

Validation of a high-performance liquid chromatography-tandem mass spectrometry immunopeptidomics assay for the identification of HLA class I ligands suitable for pharmaceutical therapies

M. Ghosh, M. Gauger, A. Marcu, A. Nelde, M. Denk, H. Schuster, H.-G. Rammensee, S. Stevanovic

The paper validates an LC-MS/MS immunopeptidomics assay for identifying HLA class I ligands suitable for personalized immunotherapy.

bioRxiv · Oct 29, 2019Immunology

TAPBPR mediates peptide dissociation from MHC class I using a leucine lever

F. T. Ilca, A. Neerincx, C. Hermann, A. Marcu, S. Stevanovic, J. E. Deane, L. H. Boyle

The paper identifies a leucine in the K22-D35 loop of TAPBPR that facilitates peptide dissociation from MHC I, revealing distinct mechanisms for peptide editing based on the C-terminal residue in the F pocket.

bioRxiv · Nov 5, 2018Immunology