Cell BiologyMolecular OncologyPeer-reviewed
Tetraploidy-linked sensitization to CENP-E inhibition in human cells
K. Yoshizawa, A. Matsura, M. Shimada…·R. Uehara
This study shows that tetraploid cells are more sensitive to CENP-E inhibitors than diploid cells, leading to selective growth suppression through mitotic delay and cohesion fatigue.
DOI 10.1002/1878-0261.13379