Author

A. McKenna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:mouse· 3 Organism:chicken / avian· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2

Frequent Co-Authors

A. Richmond· 2 shared B. W. Wren· 2 shared C. Kelly· 2 shared M. Linton· 2 shared N. Corcionivoschi· 2 shared N. Dorrell· 2 shared O. Gundogdu· 2 shared U. Lavery· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. Richmond

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Contrast-enhanced photon-counting micro-CT of tumor xenograft models

M. Li, X. Guo, A. Verma, A. Rudkouskaya, A. McKenna, X. R. M. Intes, G. Wang, M. Barroso

This study evaluates contrast agents for photon-counting micro-CT in tumor xenografts, finding that Exitrone Nano 12000 provides better vasculature enhancement and consistency compared to ISOVUE-370.

Physics in Medicine & Biology · Jul 19, 2024Peer-reviewedBioengineering

Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection.

L. Abdullah, F. E. Emiliani, C. M. Vaidya, H. Stuart, F. W. Kolling, M. E. Ackerman, L. Song, A. McKenna, Y. H. Huang

This study uses single-cell lineage tracing to show that CD8 T-cell clones exhibit differential fate commitment during acute infection, with some clones adopting memory or effector biases over time.

bioRxiv · Mar 21, 2024 · PreprintImmunology

Single-cell lineage and transcriptome reconstruction of metastatic cancer reveals selection of aggressive hybrid EMT states

K. P. Simeonov, C. N. Byrns, M. L. Clark, R. J. Norgard, B. Martin, B. Z. Stanger, A. McKenna, J. Shendure, C. J. Lengner

This study uses macsGESTALT to trace metastatic cancer lineage and transcriptomes, revealing that late-hybrid EMT states drive metastasis and are linked to poor survival in human pancreatic cancer.

bioRxiv · Aug 11, 2020Cancer Biology

Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter

A. McKenna, U. Z. Ijaz, C. Kelly, M. Linton, W. T. Sloan, B. D. Green, U. Lavery, N. Dorrell, B. W. Wren, A. Richmond, N. Corcionivoschi, O. Gundogdu

This study examines how industrial chicken production system parameters affect gut microbiome composition and Campylobacter presence, identifying links between environmental factors, microbial dynamics, and performance metrics.

bioRxiv · May 10, 2020Microbiology

Comprehensive longitudinal microbiome analysis of the chicken cecum reveals a shift from competitive to environmental drivers and a window of opportunity for Campylobacter

U. Z. Ijaz, L. Sivaloganathan, A. Mckenna, A. Richmond, C. Kelly, M. Linton, A. Stratakos, U. Lavery, A. Elmi, B. W. Wren, N. Dorrell, N. Corcionivoschi, O. Gundogdu

This study tracks the chicken cecum microbiome from day 3 to 35, identifying a shift in microbial drivers and a window for Campylobacter appearance.

bioRxiv · Jun 11, 2018Microbiology