Human KIR+CD8+ T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19
J. Li, M. E. Zaslavsky, Y. Su, M. Sikora, V. van Unen, A. Christophersen, S.-H. Chiou, L. Chen, J. Li, X. Ji, J. Wilhelmy, A. McSween, B. A. Palanski, V. Mallajosyula, G. Dhondalay, , M. Davis
The paper identifies KIR+CD8+ T cells as regulatory cells in humans that suppress pathogenic CD4+ T cells in autoimmune and infectious diseases.
bioRxiv · Dec 23, 2021 · PreprintImmunology