Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline
J. V. Graniel, K. Bisht, A. Friedman, J. White, E. Perkey, A. Vanderbeck, A. Moroz, L. J. Carrington, J. D. Brandstadter, F. Allen, A. N. Shami, P. Thomas, A. Crayton, M. Manzor, A. Mychalowych, , J. Nandakumar
This study examines the impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline, finding progressive telomere erosion and infertility without bone marrow failure.
Life Science Alliance · Oct 13, 2021Peer-reviewedCell Biology