Author

A. Moses

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:diffusion model· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Au· 1 shared A. C. Gingras· 1 shared A. G. Farias· 1 shared A. Habsid· 1 shared A. P. Amini· 1 shared A. X. Lu· 1 shared B. Andrews· 1 shared B. Derry· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Au

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TSC22D, WNK and NRBP gene families exhibit functional buffering and evolved with Metazoa for macromolecular crowd sensing

Y.-X. Xiao, S. Y. Lee, M. A. Uribe, R. Samson, A. Au, K. Yukti, Z. Liu, R. Cheng, K. Aulakh, J. Wei, A. G. Farias, T. Reilly, A. Habsid, K. Brown, K. Chan, , J. Moffat

This study identifies functional relationships between TSC22D, WNK, and NRBP gene families in macromolecular crowding sensing and cell volume regulation across metazoans.

bioRxiv · Feb 13, 2024 · PreprintCell Biology

Protein generation with evolutionary diffusion: sequence is all you need

S. Alamdari, N. Thakkar, R. van den Berg, N. Tenenholtz, B. Strome, A. Moses, A. X. Lu, N. Fusi, A. P. Amini, K. K. Yang

This paper introduces EvoDiff, a diffusion model that generates diverse, high-fidelity proteins in sequence space, overcoming limitations of structure-based models.

bioRxiv · Sep 11, 2023 · PreprintBioengineering

Coxiella burnetii small RNA 12 binds CsrA regulatory protein and transcripts for the CvpD type IV effector, regulates pyrimidine and methionine metabolism, and is necessary for optimal intracellular growth and vacuole formation during infection

S. Wachter, M. Bonazzi, K. Shifflett, A. Moses, R. Raghavan, M. F. Minnick

This study identifies CbsR12, a small RNA in Coxiella burnetii, which binds CsrA and regulates metabolic genes and a type IV effector, essential for intracellular growth and vacuole formation.

bioRxiv · Jun 21, 2019 · PreprintMicrobiology