Pharmacology & ToxicologybioRxiv
PRMT5 is a therapeutic target in choroidal neovascularization
A. Muniyandi, M. Martin, M. Sun…·T. W. Corson
This study identifies PRMT5 as a therapeutic target for neovascular age-related macular degeneration by showing its inhibition reduces NF-κB activity and angiogenic properties in ocular endothelial cells.