Author

A. Ourmazd

Primary ORCID profile (0000-0001-9946-3889 · 6 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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A. OurmazdiD6 papers · University of Wisconsin–Milwaukee

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Organism:virus· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1

Frequent Co-Authors

G. Mashayekhi· 2 shared A. Singharoy· 1 shared A. T. Bogetti· 1 shared E. Seitz· 1 shared F. Acosta-Reyes· 1 shared F. L. Kearns· 1 shared J. A. Goldsmith· 1 shared J. A. McCammon· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

G. Mashayekhi

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2 papers

Recent·Most cited

Energy Landscape of the SARS-CoV-2 Reveals Extensive Conformational Heterogeneity

G. Mashayekhi, J. Vant, A. Singharoy, A. Ourmazd

The paper uses cryo-EM to analyze the energy landscape of the SARS-CoV-2 spike protein, revealing conformational heterogeneity and dynamic behavior not captured by static models.

bioRxiv · May 11, 2021Biophysics

A glycan gate controls opening of the SARS-CoV-2 spike protein

T. E. Sztain, S.-H. Ahn, A. T. Bogetti, L. Casalino, J. A. Goldsmith, E. Seitz, R. S. McCool, F. L. Kearns, F. Acosta-Reyes, S. Maji, G. Mashayekhi, J. A. McCammon, A. Ourmazd, J. Frank, J. S. McLellan, , R. E. Amaro

This study identifies a glycan gate and key residues that facilitate SARS-CoV-2 spike protein RBD opening through simulations and experimental validation.

bioRxiv · Feb 15, 2021Biophysics