Author

A. P. Wright

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2

Frequent Co-Authors

D. A. Constant· 2 shared G. Arvidsson· 2 shared L. Sadeghi· 2 shared T. J. Nice· 2 shared A. Görgens· 1 shared A. Grandien· 1 shared A. M. Wasik· 1 shared A. Mahani· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

D. A. Constant

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Interferon Regulatory Factor 6 Determines Intestinal Epithelial Cell Development and Immunity

A. P. Wright, S. Harris, S. R. Madden, B. Ramirez Reyes, E. Mulamula, A. R. Gibson, I. Rauch, D. A. Constant, T. J. Nice

This study identifies IRF6's role in regulating intestinal epithelial cell development and innate immunity, showing it modulates antiviral responses and maintains barrier function.

bioRxiv · Jan 4, 2024Immunology

A homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium

J. A. Van Winkle, S. T. Peterson, E. A. Kennedy, M. J. Wheadon, H. Ingle, C. Desai, R. Rodgers, D. A. Constant, A. P. Wright, L. Li, M. Artyomov, S. Lee, M. T. Baldridge, T. J. Nice

The paper shows bacterial microbiota induce localized IFN-lambda-driven antiviral defenses in intestinal epithelial cells, enhancing host resistance to enteric viruses.

bioRxiv · Jun 2, 2021Immunology

Differential transcriptional reprogramming by wild type and lymphoma-associated mutant MYC proteins as B-cells convert to lymphoma-like cells

A. Mahani, G. Arvidsson, L. Sadeghi, A. Grandien, A. P. Wright

This study examines how wild-type and lymphoma-associated MYC mutants affect gene expression as B-cells transition to lymphoma-like cells, identifying distinct transcriptional changes and functional impacts.

bioRxiv · Jul 13, 2020 · PreprintCancer Biology

Differential B-cell receptor signaling requirement for adhesion of mantle cell lymphoma cells to stromal cells

l. Sadeghi, G. Arvidsson, M. Merrien, A. M. Wasik, A. Görgens, E. Smith, B. Sander, A. P. Wright

The paper identifies differential B-cell receptor signaling requirements for adhesion of mantle cell lymphoma cell lines to stromal cells, showing that inhibition of BCR signaling reduces adhesion in JeKo-1 but not REC-1 cells.

bioRxiv · Mar 6, 2020Cancer Biology