J. E. Van Eyk

This paper demonstrates that nanoparticle-based proteomics workflows enable accurate and scalable deep plasma proteomics with high precision and statistical power for biomarker discovery.

This paper introduces a high-throughput single skeletal muscle fiber proteomics method, achieving faster analysis with sufficient proteome depth compared to existing methods.

This paper introduces a dual-trap single-column configuration to improve proteomic analysis throughput by parallelizing column cleaning and sample loading, achieving high instrument utilization and reproducible quantification.

The paper identifies PDIA1 as a biomarker of β cell stress in type 1 diabetes using proteomics and validation in mouse models and human samples.

This study shows that GSNOR deficiency in mice causes preeclampsia through dysregulated placental S-nitrosylation, which can be reversed by ascorbate.