PhysiologybioRxiv
Nuclear Receptor 5A2 Regulation of Agrp underlies Olanzapine-induced Hyperphagia
R. C. Zapata, D. Zhang, A. Libster…·O. Osborn
This study identifies Nr5a2 as a key driver of olanzapine-induced hyperphagia and weight gain by directly regulating Agrp expression in the hypothalamus.
DOI 10.1038/s41380-023-01981-9