Author

O. Osborn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. J. A. Molina· 1 shared A. Libster· 1 shared A. Porcu· 1 shared A. Tao· 1 shared D. S. Herdman· 1 shared D. Zhang· 1 shared E. Raz· 1 shared F. Telese· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. J. A. Molina

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nuclear Receptor 5A2 Regulation of Agrp underlies Olanzapine-induced Hyperphagia

R. C. Zapata, D. Zhang, A. Libster, A. Porcu, P. Montilla-Perez, Z. Zhang, S. M. Correa, F. Telese, O. Osborn

This study identifies Nr5a2 as a key driver of olanzapine-induced hyperphagia and weight gain by directly regulating Agrp expression in the hypothalamus.

bioRxiv · Feb 15, 2022Physiology

Gnas ablation in CD11c+ cells prevents high-fat diet-induced obesity by elevating adipose tissue catecholamine levels and thermogenesis

L. Zeng, D. S. Herdman, J. Lee, A. Tao, M. Das, S. Bertin, L. Eckmann, S. K. Mahata, S. Devulapalli, H. Patel, A. J. A. Molina, O. Osborn, M. Corr, E. Raz, N. J. G. Webster

bioRxiv · Jan 27, 2022 · PreprintImmunology

Tankyrase interacts with the allosteric site of glucokinase and inhibits its glucose-sensing function in the beta cell

N.-W. Chi, T. Eisemann, T.-Y. J. Yeh, S. Roy, T. J. Chi, S. H. Lu, J. M. Pascal, O. Osborn

This study identifies tankyrase (TNKS) as a physiological inhibitor of glucokinase (GCK) in pancreatic beta cells by trapping it in an inactive conformation.

bioRxiv · Aug 8, 2021 · PreprintCell Biology