A. Richards

SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection

This study infects human pluripotent stem cell-derived vascular cells with SARS-CoV-2 and finds that smooth muscle cells drive vascular inflammation and coagulation.

The microenvironment dictates glycocalyx construction and immune surveillance

This study shows that the physical properties of the microenvironment influence glycocalyx composition and immune surveillance in vitro using physiologically relevant models.

The oomycete MAMP, arachidonic acid, and an Ascophyllum nodosum-derived plant biostimulant induce defense metabolome remodeling in tomato

This study investigates how arachidonic acid and a seaweed-derived biostimulant alter the metabolome of tomato plants, revealing shared defense-related metabolic changes.

SVDquintets: a New Tool for Species Tree Inference

The paper introduces SVDquintets, a species tree inference algorithm that improves upon SVDQuartets by extending rank results to five species, showing better performance in simulated data.

CD39 Identifies Tumor-Reactive CD8 T cells in Patients With Lung Cancer

This study identifies CD39 as a marker for tumor-reactive CD8 T cells in lung cancer, showing its association with clinical outcomes and response to immune checkpoint therapy.

Site Pattern Probabilities Under the Multispecies Coalescent and a Relaxed Molecular Clock: Theory and Applications

This paper generalizes site pattern probabilities under the multispecies coalescent to a relaxed molecular clock model, improving phylogenetic inference when mutation rates vary across species.

Comparative Analysis of T Cell Spatial Proteomics and the Influence of HIV Expression

The paper compares machine learning methods for spatial proteome classification in HIV-expressing T cells and identifies Nef-dependent interactors.