Author

A. Rojo-Sebastian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Moreno-Bueno· 3 shared D. Sarrio· 2 shared L. Martinez· 2 shared A. Jimenez-Segovia· 1 shared A. Molina-Crespo· 1 shared A. Mota· 1 shared A. Rynne-Vidal· 1 shared A. TEIJO· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

G. Moreno-Bueno

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3 papers

Recent·Most cited

Cancer BiologyJournal of Experimental & Clinical Cancer ResearchPeer-reviewedSep 26, 2022

Gasdermin B over-expression arbitrates HER2-targeted therapy resistance by inducing protective autophagy

M. Gamez-Chiachio, A. Molina-Crespo, C. Ramos-Nebot…·G. Moreno-Bueno

This study identifies GSDMB over-expression as a driver of HER2-targeted therapy resistance through autophagy induction and shows that combining lapatinib with chloroquine enhances therapeutic efficacy in GSDMB-positive tumors.

DOI 10.1186/s13046-022-02497-w

humanmouse

𝕏 PostBluesky

Cancer BiologybioRxivMay 27, 2021

IN VIVO ANALYSIS OF THE ROLE OF GASDERMIN-B (GSDMB) IN CANCER USING NOVEL KNOCK-IN MOUSE MODELS

D. SARRIO, A. ROJO-SEBASTIAN, A. TEIJO…·G. MORENO-BUENO

This study uses novel knock-in mouse models to investigate GSDMB2's role in cancer, finding it does not significantly drive tumorigenesis but may reduce gastric carcinogenesis.

DOI 10.3389/fcell.2022.813929

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivSep 18, 2018

Prostaglandin F2α-induced TGFβ-PMEPA1 pathway is a critical mediator of epithelial plasticity and ovarian carcinoma progression.

A. Jimenez-Segovia, A. Mota, A. Rojo-Sebastian…·K. Stamatakis

This paper identifies PGF2α-induced TGFβ-PMEPA1 pathway as a driver of epithelial plasticity and ovarian cancer progression, with PMEPA1 as a therapeutic target and prognostic biomarker.

DOI 10.1016/j.neo.2019.10.001

mousehuman

𝕏 PostBluesky