Cell BiologybioRxiv
Force-dependent recruitment of Piezo1 drives focal adhesion maturation and calcium entry in normal but not tumor cells
M. Yao, A. S. Tijore, D. Cheng…·M. Sheetz
The paper shows Piezo1 binds to matrix adhesions in a force-dependent manner in normal cells, promoting adhesion maturation and calcium entry, but not in tumor cells.
DOI 10.1126/sciadv.abo1461