Author

A. Saiardi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Plant Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 3 Research Focus:metabolism & bioenergetics· 3 Assay:metabolomics· 3 Assay:proteomics· 3 Organism:Arabidopsis· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

D. Fiedler· 4 shared H. J. Jessen· 4 shared D. Qiu· 3 shared G. Schaaf· 3 shared D. Laha· 2 shared E. Riemer· 2 shared G. Liu· 2 shared N. P. Laha· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersBiochemistry

D. Fiedler

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Phosphate overplus response in Chlamydomonas reinhardtii: polyphosphate dynamics to monitor phosphate uptake and turnover

T. Zuniga-Burgos, A. Saiardi, M. A. Camargo-Valero, A. Baker

This paper quantifies polyphosphate dynamics in Chlamydomonas reinhardtii during phosphate deprivation and resupply to optimize phosphate overplus response and nutrient recovery.

bioRxiv · Jan 25, 2024Microbiology

β-Lapachone Regulates Mammalian Inositol Pyrophosphate Levels in an NQO1- and Oxygen-dependent Manner

V. B. Eisenbeis, D. Qiu, L. Strotmann, G. Liu, I. Prucker, K. Ritter, C. Loenarz, A. Saiardi, H. J. Jessen

This study shows β-lapachone reduces inositol pyrophosphate levels in mammalian cells through NQO1-dependent oxygen activation and ROS production.

bioRxiv · Nov 27, 2022Biochemistry

Stable isotopomers of myo-inositol to uncover the complex MINPP1-dependent inositol phosphate network

M. Nguyen Trung, S. Kieninger, Z. Fandi, D. Qiu, G. Liu, A. Saiardi, H. Jessen, B. Keller, D. Fiedler

The paper uses stable isotopomers of myo-inositol to analyze the MINPP1-dependent inositol phosphate network in human cells, revealing a novel dephosphorylation branch.

bioRxiv · Aug 29, 2022 · PreprintBiochemistry

Inositol pyrophosphate-controlled kinetochore architecture and mitotic entry in S. pombe

N. A. Kuenzel, A. R. Alcazar-Roman, A. Saiardi, S. M. Bartsch, S. Daunaraviciute, D. Fiedler, U. Fleig

This study shows that IP8, regulated by Asp1, controls kinetochore architecture and mitotic entry in S. pombe by modulating spindle dynamics and chromosome segregation fidelity.

bioRxiv · Aug 8, 2022Cell Biology

Analysis of Inositol Phosphate Metabolism by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry (CE-ESI-MS)

D. Qiu, M. S. Wilson, V. B. Eisenbeis, R. Harmel, E. Riemer, T. M. Haas, C. Wittwer, N. Jork, C. Gu, S. B. Shears, G. Schaaf, B. Kammerer, D. Fiedler, A. Saiardi, H. J. Jessen

This paper develops a CE-ESI-MS method to analyze inositol phosphates and pyrophosphates, revealing unknown synthesis pathways in mammals.

bioRxiv · Aug 27, 2020Biochemistry

ITPK1 is an InsP6/ADP phosphotransferase that controls systemic phosphate homeostasis in Arabidopsis

E. Riemer, D. Laha, R. K. Harmel, P. Gaugler, V. Pries, M. Frei, M. R. Hajirezaei, N. P. Laha, L. Krusenbaum, R. Schneider, H. J. Jessen, A. Saiardi, D. Fiedler, G. Schaaf, R. F. H. Giehl

This study shows ITPK1 generates PP-InsPs from InsP6 and regulates phosphate homeostasis in Arabidopsis by controlling InsP7 and InsP8 synthesis.

bioRxiv · May 18, 2020Plant Biology

ITPK1-Dependent Inositol Polyphosphates Regulate Auxin Responses in Arabidopsis thaliana

N. P. Laha, Y. W. Dhir, R. F. H. Giehl, E. M. Schaefer, P. Gaugler, Z. H. Shishavan, H. Gulabani, H. Mao, N. Zheng, N. von Wiren, H. J. Jessen, A. Saiardi, S. Bhattacharjee, D. Laha, G. Schaaf

This study shows that ITPK1 produces 5-InsP7, which binds to auxin receptors and influences plant growth responses.

bioRxiv · Apr 23, 2020 · PreprintPlant Biology