Cancer BiologybioRxivPreprint
Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)
D. Weichenhan, A. Riedel, E. Sollier…·C. Plass
The paper shows MNX1 overexpression in t(7;12)(q36;p13) AML is due to enhancer hijacking, not oncofusion, and is common in pediatric cases.
DOI 10.1101/2023.09.13.557546