Author

A. Waraky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. Plass· 2 shared D. Weichenhan· 2 shared J. Hey· 2 shared L. Palmqvist· 2 shared M. Baehr· 2 shared P. Lutsik· 2 shared A. Dolnik· 1 shared A. Oestlund· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

C. Plass

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2 papers

Recent·Most cited

Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)

D. Weichenhan, A. Riedel, E. Sollier, U. H. Toprak, J. Hey, K. Breuer, J. A. Wierzbinska, A. Touzart, P. Lutsik, M. Baehr, A. Oestlund, C. Nilsson, S. Jacobsson, M. Edler, A. Waraky, , C. Plass

The paper shows MNX1 overexpression in t(7;12)(q36;p13) AML is due to enhancer hijacking, not oncofusion, and is common in pediatric cases.

bioRxiv · Sep 13, 2023 · PreprintCancer Biology

Aberrant MNX1 Expression Associated with t(7;12)(q36;p13) Pediatric Acute Myeloid 1 Leukemia Induces the Disease Through Altering Histone Methylation

A. Waraky, A. Ostlund, T. Nilsson, D. Weichenhan, P. Lutsik, M. Baehr, J. Hey, J. Adamsson, M. H. A. Morsy, S. Li, L. Fogelstrand, C. Plass, L. Palmqvist

This study identifies MNX1 as a driver of t(7;12)(q36;p13) pediatric AML by altering histone methylation and shows that targeting MNX1 can prevent leukemia development.

bioRxiv · Jun 10, 2022Cancer Biology