Author

A. Trauner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

S. Borrell· 4 shared S. Gagneux· 4 shared C. Loiseau· 3 shared J. Feldmann· 3 shared C. Beisel· 2 shared M. Reinhard· 2 shared A. Banaei-Esfahani· 1 shared A. Hall· 1 shared

Activity by Year

2018-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

S. Borrell

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Evolution of Fluoroquinolone-Resistance in Mycobacterium tuberculosis is Modulated by the Genetic Background

R. A. D. Castro, A. Ross, L. Kamwela, M. Reinhard, C. Loiseau, J. Feldmann, S. Borrell, A. Trauner, S. Gagneux

This study shows that the genetic background of Mycobacterium tuberculosis significantly affects the evolution of fluoroquinolone resistance in both in vitro experiments and clinical isolates.

bioRxiv · Jun 3, 2019Microbiology

Resource misallocation as a mediator of fitness costs in antibiotic resistance.

A. Trauner, A. Banaei-Esfahani, S. M. Gygli, P. Warmer, J. Feldmann, S. Shafieechashmi, K. Eschbach, M. Zampieri, S. Borrell, B. C. Collins, C. Beisel, R. Aebersold, S. Gagneux

The paper investigates the fitness cost of rifampicin resistance in Mycobacterium tuberculosis using transcriptomic and proteomic profiling, finding that aberrant gene expression causes the cost and that this burden can be suppressed.

bioRxiv · Nov 27, 2018 · PreprintMicrobiology

Transition bias influences the evolution of antibiotic resistance in Mycobacterium tuberculosis

J. L. Payne, F. Menardo, A. Trauner, S. Borrell, S. Gygli, C. Loiseau, S. Gagneux, A. Hall

The paper shows transition bias drives antibiotic resistance mutations in Mycobacterium tuberculosis, suggesting mutation supply, not selection, is the cause.

bioRxiv · Sep 20, 2018Evolutionary Biology

Reference Set of Mycobacterium tuberculosis Clinical Strains: A tool for research and product development

S. Borrell, A. Trauner, D. Brites, L. Rigouts, C. Loiseau, M. Coscolla, S. Niemann, B. De Jong, D. Yeboah-Manu, M. Kato-Maeda, J. Feldmann, M. Reinhard, C. Beisel, S. Gagneux

The paper introduces a reference set of 20 genetically characterized Mycobacterium tuberculosis clinical strains to enhance TB research by incorporating phylogenetic diversity beyond the commonly used lab strains.

bioRxiv · Aug 25, 2018Microbiology