BiochemistrybioRxiv
Structural basis for lysophosphatidylserine recognition by GPR34
T. Izume, R. Kawahara, A. Uwamizu…·O. Nureki
This study presents cryo-EM structures of GPR34-Gi complex bound with LysoPS analogs, revealing ligand recognition mechanisms and identifying 2-acyl LysoPS as the physiological ligand.