MicrobiologybioRxivPreprint
A comparative analysis of SARS-CoV-2 antivirals in human airway models characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19
M. de Vries, A. Mohamed, R. A. Prescott…·M. Dittmann
This study compares the antiviral efficacy of PF-00835231, GC-376, and remdesivir in human airway models, showing PF-00835231 is at least as potent as the others and not affected by P-glycoprotein efflux.
DOI 10.1101/2020.08.28.272880